substance abuse20 min readOctober 7, 2024

Kratom Withdrawal: Symptoms, Duration, and Treatment Guide

Robin Campbell, LMFT, PHD Kratom Withdrawal: Symptoms, Duration, and Treatment Guide Kratom withdrawal can be a challenging experience for individuals who have developed a dependence on this herbal remedy, often used to relieve pain and manage mental health…

Buddy Clay

Clinical Editorial Team

    Kratom Withdrawal: Symptoms, Duration, and Treatment Guide

    Kratom withdrawal can be a challenging experience for individuals who have developed a dependence on this herbal remedy, often used to relieve pain and manage mental health symptoms, leading to kratom dependence. As the opioid epidemic continues to affect many, kratom use has become increasingly common, leading to a rise in kratom use disorder. Understanding the withdrawal process is crucial for those seeking to overcome kratom addiction and avoid the severe symptoms associated with withdrawal syndrome. The withdrawal timeline can vary, with users experiencing a range of physical and mental symptoms, including abdominal pain, runny nose, and depressed mood. With support from healthcare providers and effective treatment options, including medication-assisted treatment, individuals can navigate this difficult journey toward recovery in a safe and supportive environment.

    What is Kratom?

    Kratom, scientifically known as Mitragyna speciosa, is a tropical evergreen tree native to Southeast Asia, particularly in countries like Thailand, Indonesia, and Malaysia. Its leaves contain compounds that can produce stimulant effects at low doses and sedative effects at higher doses, making it popular for various purposes, including pain relief, mood enhancement, and anxiety reduction. Traditionally, kratom leaves were chewed or brewed into tea, but today, it is commonly available in powdered form, capsules, and extracts. Despite its growing popularity, kratom has garnered significant attention due to concerns about its safety, potential for addiction, and regulatory status, as it is classified as a controlled substance in some regions. Ongoing research aims to better understand its effects, benefits, and risks, particularly in the context of opioid use disorder and its potential therapeutic properties.

    What is Kratom Withdrawal?

    Kratom withdrawal refers to the physical and psychological symptoms that can occur when a person who regularly uses kratom suddenly reduces or stops its intake. As kratom acts on the same brain receptors as opioids, individuals may develop a dependence on the substance, leading to withdrawal symptoms similar to those associated with opioid withdrawal. While some individuals may experience severe symptoms, others may only face moderate withdrawal symptoms that still require medical attention. These symptoms can vary in intensity and may include irritability, anxiety, insomnia, muscle aches, nausea, vomiting, and fatigue. The onset of withdrawal typically begins within a day or two after the last dose and can last for several days to weeks, depending on the individual’s usage patterns and overall health. Due to the potential for withdrawal symptoms, it is crucial for individuals seeking to stop kratom use to consider a gradual tapering approach and seek support from healthcare professionals to manage their symptoms effectively.

    Kratom Uses for Pain Relief

    Kratom has been used for various purposes, primarily for its stimulant and sedative effects, depending on the dosage. Here are some common uses of kratom:

    1. 1Pain Relief: Many users report that kratom can alleviate chronic pain, making it a popular alternative for those seeking relief from conditions like arthritis, back pain, and fibromyalgia.
    1. 1Mood Enhancement: At lower doses, kratom may enhance mood and promote feelings of euphoria, making it appealing for individuals dealing with depression or anxiety.
    1. 1Energy Boost: Some users take kratom for its stimulant properties, which can increase energy levels, focus, and alertness, similar to caffeine.
    1. 1Anxiety Reduction: Kratom has been used to help reduce anxiety and promote relaxation, although the effects can vary depending on the individual and dosage.
    1. 1Opioid Withdrawal Relief: Some individuals turn to kratom as a means of managing withdrawal symptoms from opioids, as it may help ease cravings and discomfort during detoxification.
    1. 1Cough Suppressant: Traditional uses in Southeast Asia include employing kratom for its cough-suppressing properties.
    1. 1Social Interactions: Some users consume kratom to promote sociability and reduce social anxiety, facilitating interactions in social settings.

    Types of Kratom

    Kratom is available in various types, often categorized by the color of the veins in the leaves. Each type is associated with different effects:

    1. 1Red Vein Kratom: Known for its calming and sedative effects, often used for pain relief and anxiety reduction. Street names include “Red Bali” and “Red Borneo.”
    1. 1Green Vein Kratom: Offers a balanced effect, providing mild stimulation and pain relief. Commonly referred to as “Green Malay” or “Green Maeng Da.”
    1. 1White Vein Kratom: Associated with stimulating effects, enhancing energy and focus. Street names include “White Thai” and “White Borneo.”
    1. 1Yellow Vein Kratom: A less common type, often a blend of other strains, known for its mood-enhancing and mild energizing effects. Street names might include “Yellow Vietnam” or “Yellow Horn.”

    These strains can be found in various forms, including powders, capsules, and extracts, and are often marketed under various street names based on their origins or effects.

    Efficacy of Kratom

    The efficacy of kratom is a topic of ongoing debate and research. Many users report positive effects, such as pain relief, improved mood, and increased energy, particularly with certain strains. However, scientific studies are limited, and the variability in individual responses complicates the assessment of its overall effectiveness. Some research suggests that kratom may have potential benefits for managing pain and alleviating opioid withdrawal symptoms, but concerns about safety, potential for addiction, and withdrawal symptoms warrant caution. Regulatory agencies like the FDA have expressed skepticism regarding kratom’s safety and efficacy, urging further research to understand its effects fully. As a result, while some users find kratom beneficial, its long-term efficacy and safety remain uncertain.

    How Does Kratom Work on the Body and Brain?

    Kratom works on the body and brain primarily by interacting with opioid receptors, particularly the mu-opioid receptors, similar to traditional opioids. The active compounds in kratom, mainly mitragynine and 7-hydroxymitragynine, bind to these receptors, leading to various effects depending on the dosage. At low doses, kratom tends to produce stimulant effects, increasing energy and alertness. At higher doses, it can have sedative effects, providing pain relief and relaxation. Additionally, kratom may influence other neurotransmitter systems, such as serotonin and dopamine, which can affect mood and emotional regulation. However, the exact mechanisms and long-term effects are still not fully understood, and further research is needed to clarify its impact on the body and brain.

    Onset and Duration

    The onset and duration of kratom’s effects vary based on the dosage, strain, and individual metabolism. Typically, users report that effects begin within 20 to 60 minutes after ingestion. For lower doses, stimulant effects may last around 2 to 4 hours, while higher doses can produce sedative effects lasting 4 to 6 hours or more. The specific strain can also influence these factors; for instance, red vein kratom may have longer-lasting effects compared to white vein varieties. Individual factors, such as tolerance, overall health, and method of consumption, can further affect how quickly and for how long kratom’s effects are felt.

    How Long Does Kratom Stay in Your System?

    The half-life of kratom refers to the time it takes for half of the active compounds, primarily mitragynine and 7-hydroxymitragynine, to be eliminated from the body. While specific studies on kratom’s half-life are limited, estimates suggest that the half-life of mitragynine is approximately 3.5 hours, although this can vary based on individual factors such as metabolism, age, weight, and overall health. Consequently, the effects of kratom may diminish within a few hours, but the duration can be influenced by the dosage and strain used. Understanding the half-life is essential for users who are considering regular consumption or tapering off, as it can provide insight into how frequently they might experience the substance’s effects and how long it remains in their system.

    How Long is Kratom Detectable?

    Kratom can be detectable in the body for varying lengths of time, depending on several factors such as the method of testing, dosage, frequency of use, and individual metabolism. Here’s a general overview of how long kratom is detectable in different types of tests:

    • Urine Tests: Kratom is typically detectable in urine for up to 7 days after use. However, this window can be shorter for infrequent users and longer for those who use it regularly.
    • Blood Tests: In blood tests, kratom can usually be detected for about 24 hours post-consumption.
    • Saliva Tests: Kratom may be detectable in saliva for approximately 1 to 3 days.
    • Hair Tests: In hair follicle tests, kratom can potentially be detectable for up to 90 days, similar to many other substances.

    Signs and Kratom Withdrawal Symptoms

    Kratom withdrawal can manifest a range of physical and psychological symptoms, particularly in individuals who have developed a dependence on the substance. Common signs and symptoms of kratom withdrawal include:

    Physical Symptoms:

    • Muscle aches and pains
    • Fatigue and weakness
    • Nausea and vomiting
    • Diarrhea
    • Sweating and chills
    • Insomnia or disrupted sleep patterns

    Psychological Symptoms:

    • Irritability and agitation
    • Anxiety or heightened anxiety levels
    • Mood swings or depression
    • Cravings for kratom

    Cognitive Symptoms:

    • Difficulty concentrating
    • Confusion or foggy thinking

    Understanding the behaviors linked to drug abuse is crucial for recognizing the signs of kratom withdrawal and seeking appropriate help.

    Withdrawal symptoms can begin within a day or two after the last dose and may last for several days to weeks, depending on the individual’s usage patterns and overall health. The intensity and duration of symptoms can vary widely, making it crucial for those looking to stop kratom use to consider a gradual tapering approach and seek professional support if needed.

    How Long Does Kratom Withdrawal Last?

    Kratom withdrawal duration can vary significantly among individuals, typically lasting from a few days to several weeks. Symptoms often begin within 24 to 48 hours after the last dose, peaking around the second or third day. Most physical symptoms generally subside within a week, while psychological symptoms, such as cravings and mood disturbances, may persist for a longer period, potentially lasting up to two weeks or more. The overall length and intensity of withdrawal can be influenced by factors like the dosage used, frequency of consumption, and individual metabolism.

    Kratom Withdrawal Timeline

    The kratom withdrawal timeline can vary depending on several factors, including the individual’s level of kratom use, the duration of use, and the method of consumption. Generally, kratom withdrawal symptoms can start within 12 to 48 hours after the last dose and can last anywhere from 3 to 5 days. However, some individuals may experience withdrawal symptoms for up to a week or more.

    The timeline of kratom withdrawal can be broken down into several stages:

    • Stage 1 (12-24 hours): Mild withdrawal symptoms such as anxiety, irritability, and insomnia may start to appear. During this initial phase, individuals might also experience muscle aches and a runny nose, similar to the early stages of opioid withdrawal.
    • Stage 2 (24-48 hours): Withdrawal symptoms can intensify, including stomach discomfort, sweating, and tremors. This stage often brings more pronounced physical symptoms, such as nausea and vomiting, as the body reacts to the absence of kratom.
    • Stage 3 (48-72 hours): Peak withdrawal symptoms can occur, including severe anxiety, depression, and physical discomfort. This is often the most challenging phase, with individuals experiencing heightened cravings and significant mood disturbances.
    • Stage 4 (72 hours and beyond): Withdrawal symptoms can start to subside, but some individuals may experience lingering symptoms such as fatigue and mood swings. Psychological symptoms like anxiety and depression may persist, requiring ongoing support and management.

    Understanding the kratom withdrawal timeline can help individuals prepare for the process and seek appropriate support to manage their symptoms effectively.

    Side Effects and Risks of Kratom Withdrawal

    Short-Term Side Effects of Kratom Withdrawal:

    • Physical Symptoms: Muscle aches, fatigue, nausea, vomiting, diarrhea, sweating, and chills.
    • Psychological Symptoms: Irritability, anxiety, mood swings, and cravings.
    • Cognitive Issues: Difficulty concentrating and foggy thinking.

    These symptoms can lead to significant discomfort and may require medical support to manage effectively. Recognizing drug and alcohol dependence is essential for addressing the long-term risks associated with kratom withdrawal.

    Long-Term Risks of Kratom Withdrawal:

    • Psychological Impact: Prolonged anxiety and depression can emerge, particularly for individuals who used kratom to self-medicate.
    • Relapse Potential: Individuals may experience strong cravings, increasing the risk of relapse into kratom use or seeking out other substances.
    • Dependence on Other Substances: Some users may turn to other drugs, including opioids or stimulants, to cope with withdrawal symptoms or emotional distress.
    • Social and Occupational Consequences: Ongoing psychological symptoms and cravings can affect personal relationships, job performance, and overall quality of life.

    Is Kratom Addictive?

    Yes, kratom can be addictive. While some users initially take kratom for its stimulating and pain-relieving effects, regular use can lead to physical dependence and addiction. Users may develop tolerance, requiring larger doses to achieve the same effects, and may experience withdrawal symptoms when they try to reduce or stop consumption. The potential for addiction is particularly concerning given kratom’s interaction with opioid receptors in the brain, leading to effects similar to those of traditional opioids. As a result, individuals using kratom should approach it with caution and be aware of the risks associated with long-term use. Understanding alcohol dependence alongside kratom addiction can provide a more comprehensive approach to treatment and recovery.

    Can You Overdose on Kratom?

    Yes, it is possible to overdose on kratom, especially at high doses or when combined with other substances. Symptoms of kratom overdose may include severe nausea, vomiting, dizziness, respiratory depression, and in extreme cases, seizures or loss of consciousness. The risk of overdose increases with higher doses and frequent use, as well as when kratom is taken alongside other drugs or alcohol. While fatalities directly attributed to kratom are rare, caution is advised, and individuals should be aware of the potential dangers associated with excessive use.

    Kratom Detox and Tapering

    Kratom detox and tapering are two approaches to managing kratom withdrawal symptoms. Detox involves the complete cessation of kratom use, while tapering involves gradually reducing the dose of kratom over a period of time.

    Detox is often recommended for individuals who have been using kratom heavily or for an extended period. However, detox can be challenging, and withdrawal symptoms can be severe. This approach requires a strong support system and, ideally, medical supervision to ensure safety and comfort.

    Tapering, on the other hand, can be a more gradual and comfortable approach to managing withdrawal symptoms. This method involves reducing the dose of kratom by a small amount each day, allowing the body to adjust to the decrease in kratom levels. Tapering can help minimize withdrawal symptoms and make the transition to a kratom-free lifestyle easier. It is often recommended for individuals who prefer a less abrupt cessation and want to reduce the risk of severe withdrawal symptoms.

    Both detox and tapering have their benefits and challenges, and the best approach depends on the individual’s specific situation and health status. Consulting with a healthcare provider can help determine the most appropriate method for managing kratom withdrawal.

    Medical Detox for Kratom Withdrawal

    Medical detox for kratom withdrawal involves the use of medications and medical supervision to manage withdrawal symptoms. This approach is often recommended for individuals who have been using kratom heavily or for an extended period, as well as those who have a history of addiction or substance abuse.

    Medical detox for kratom withdrawal typically involves the use of medications such as buprenorphine or clonidine to manage withdrawal symptoms. These medications can help reduce the severity of withdrawal symptoms and make the detox process more comfortable. Buprenorphine, for example, is an opioid partial agonist that can help alleviate cravings and reduce withdrawal symptoms, while clonidine can help manage symptoms like anxiety and agitation.

    In addition to medication, medical detox for kratom withdrawal may also involve counseling and therapy to address underlying issues related to kratom use. This can include cognitive-behavioral therapy (CBT), motivational interviewing (MI), and contingency management (CM). These therapeutic approaches can help individuals develop coping strategies, address triggers for kratom use, and build a foundation for long-term recovery.

    Medical detox provides a structured and supportive environment for individuals to safely navigate the withdrawal process, reducing the risk of complications and increasing the likelihood of successful recovery.

    Medications for Kratom Withdrawal

    There are several medications that can be used to manage kratom withdrawal symptoms. These medications can help reduce the severity of withdrawal symptoms and make the detox process more comfortable.

    Some of the medications that may be used to manage kratom withdrawal symptoms include:

    • Buprenorphine: This medication is an opioid partial agonist that can help reduce the severity of withdrawal symptoms. It works by binding to the same receptors in the brain as kratom, helping to alleviate cravings and reduce withdrawal discomfort.
    • Clonidine: This medication is an alpha-2 adrenergic agonist that can help reduce the severity of withdrawal symptoms. It is particularly effective in managing symptoms like anxiety, agitation, and muscle aches.
    • Lofexidine: Similar to clonidine, lofexidine is an alpha-2 adrenergic agonist that can help reduce the severity of withdrawal symptoms. It is often used to manage symptoms such as sweating, chills, and restlessness.
    • Hydroxyzine: This medication is an antihistamine that can help reduce the severity of withdrawal symptoms. It is commonly used to manage symptoms like anxiety, nausea, and insomnia.

    It’s essential to note that these medications should only be used under the guidance of a medical professional, as they can have side effects and interact with other medications. A healthcare provider can help determine the most appropriate medication and dosage based on the individual’s specific needs and health status.

    Kratom and Opioid Withdrawal

    Kratom has been promoted as a treatment for opioid withdrawal, but its effectiveness is still unclear. Some studies suggest that kratom may help reduce the severity of opioid withdrawal symptoms, while others have found no significant benefit.

    Kratom works by interacting with opioid receptors in the brain, which can help reduce the severity of withdrawal symptoms. This interaction can provide some relief from the physical and psychological symptoms associated with opioid withdrawal, such as muscle aches, anxiety, and cravings. However, kratom can also produce withdrawal symptoms of its own, which can make it challenging to manage opioid withdrawal.

    In addition, kratom can interact with other medications used to treat opioid addiction, such as buprenorphine and methadone. This can increase the risk of adverse effects and reduce the effectiveness of these medications. For example, combining kratom with buprenorphine can lead to increased sedation and respiratory depression, posing significant health risks.

    Overall, while kratom may have some potential benefits in managing opioid withdrawal symptoms, its use should be approached with caution. Individuals should consult with a medical professional before using kratom for this purpose to ensure it is safe and appropriate for their specific situation.

    Alcohol Use While Going Through Kratom Withdrawal

    Using alcohol while going through kratom withdrawal is strongly discouraged due to several risks. Both substances can affect the central nervous system, potentially leading to increased sedation, respiratory depression, and heightened risk of overdose. Alcohol may also exacerbate withdrawal symptoms, intensifying anxiety, irritability, and mood swings. Additionally, using alcohol as a coping mechanism during withdrawal can lead to further substance dependence, complicating recovery efforts. It’s crucial for individuals in kratom withdrawal to seek healthier coping strategies and consider professional support to navigate their symptoms safely.

    Treatment Options for Kratom Withdrawal

    Treatment options for kratom withdrawal typically focus on managing symptoms and supporting recovery. These options include:

    1. 1Medical Supervision: Consulting a healthcare provider for guidance and potential medication to ease withdrawal symptoms, such as anti-anxiety medications or pain relievers.
    1. 1Gradual Tapering: Slowly reducing kratom intake to minimize withdrawal severity, often under medical supervision.
    1. 1Counseling and Therapy: Engaging in cognitive-behavioral therapy (CBT) or support groups to address underlying issues, cravings, and coping strategies.
    1. 1Nutritional Support: Maintaining a balanced diet and staying hydrated to help the body recover.
    1. 1Holistic Approaches: Utilizing practices like mindfulness, meditation, or yoga to promote mental well-being and stress reduction.
    1. 1Rehabilitation Programs: In more severe cases, enrolling in a substance abuse treatment program for comprehensive support.

    Medication-assisted treatment, commonly used in treating opioid use disorder, can also be effective in managing kratom withdrawal symptoms.

    Does Insurance Cover Treatment?

    Whether insurance covers treatment for kratom withdrawal can vary significantly based on the individual’s insurance plan and the type of treatment sought. Many health insurance plans provide coverage for substance use treatment, including inpatient rehab, outpatient therapy, and counseling services, especially if they are medically necessary. However, since kratom is not classified as a controlled substance in many areas, specific coverage for kratom withdrawal may depend on the treatment facility and the diagnosis provided. It’s important for individuals to check with their insurance provider to understand their coverage options and any out-of-pocket costs associated with treatment.

    Common Insurance Options for Kratom Withdrawal Treatment

    Common insurance options for kratom withdrawal treatment typically include:

    1. 1Private Health Insurance: Many private insurance plans cover substance use disorder treatment, including therapy, counseling, and rehabilitation programs. Coverage details can vary widely.
    1. 1Medicaid: This state and federal program may cover treatment for individuals with low income, including outpatient and inpatient services for substance use disorders.
    1. 1Medicare: For eligible seniors, Medicare may cover certain treatment services for substance abuse, including counseling and outpatient care.
    1. 1Employee Assistance Programs (EAPs): Some employers offer EAPs that provide counseling and referral services for substance use issues, often at no cost to employees.
    1. 1Substance Abuse Treatment Programs: Facilities that specialize in addiction treatment may offer financing options or sliding scale fees for those without insurance.

    Conclusion

    In conclusion, navigating kratom withdrawal involves recognizing the signs of drug dependence and understanding the various withdrawal symptoms that can occur. From mild symptoms like joint pain to more severe psychological withdrawal symptoms, it’s essential to approach this process with the right support and resources. The Food and Drug Administration (FDA) and the Drug Enforcement Administration (DEA) continue to evaluate the implications of kratom use, emphasizing the importance of treating addiction effectively. By leveraging FDA-approved medications and maintaining open communication with healthcare providers, individuals can better manage their withdrawal experience and work towards long-term recovery from kratom misuse. As awareness grows, it is vital for those affected by kratom use disorder to seek help and explore effective treatment pathways to reclaim their mental health and well-being.

    Seeking Treatment? We Can Help!

    At New Hope Healthcare, as an in-network provider we work with most insurance plans, such as:

    • First Health Network
    • Aetna
    • Humana
    • TriWest VA
    • UMR
    • Oscar
    • Celtic Insurance
    • And More

    If you or a loved one are struggling with mental health challenges or substance abuse, reach out to New Hope Healthcare today. Our team of compassionate professionals is here to support your journey towards lasting well-being. Give us a call at 866-799-0806. Visit SAMHSA for more information.

    Frequently Asked Questions

    What are the common symptoms of kratom withdrawal?

    Common symptoms include muscle aches, fatigue, nausea, vomiting, diarrhea, irritability, anxiety, mood swings, and cravings.

    How long does kratom withdrawal last?

    Withdrawal symptoms typically begin within 24 to 48 hours after the last dose and can last from a few days to several weeks, depending on the individual’s usage patterns.

    Is kratom withdrawal dangerous?

    While kratom withdrawal is generally not life-threatening, it can be uncomfortable and may lead to significant psychological distress, making professional support advisable.

    Can I use medications to help with withdrawal?

    Yes, medications such as anti-anxiety drugs or pain relievers may be prescribed to help manage withdrawal symptoms, but this should be done under medical supervision.

    What treatment options are available for kratom withdrawal?

    Treatment options include gradual tapering of use, counseling, therapy, medical supervision, nutritional support, and rehabilitation programs for more comprehensive care.

    About the Author

    Buddy Clay

    Buddy Clay

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