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Opana vs. Roxicodone: Analysis of Prescription Opioids

Clinically Reviewed by: Dr. Robin Campbell, LMFT, PHD

Empowering individuals on their journey to addiction recovery is our mission at New Hope Healthcare Institute, located in Knoxville, TN. Our specialized programs cater to both teens and adults who grapple with dual diagnoses, providing them with the tools and support needed for lasting recovery. In this extensive guide, we will delve deeper into the intricate differences between Opana and Roxicodone, two widely prescribed opioids. By understanding these distinctions, you can make informed choices regarding your path to addiction recovery.

A Detailed Examination of Opana and Roxicodone:

Opana (oxymorphone) and Roxicodone (oxycodone) belong to the same class of opioid analgesics and are typically prescribed to manage various levels of pain, ranging from moderate to severe. It is essential to note that these medications should be used only under the strict supervision of a healthcare professional.

Exploring the Nuances:

  • Active Ingredient: Opana contains oxymorphone as its primary active ingredient, while Roxicodone features oxycodone as its primary active compound.
  • Potency: In terms of potency, Opana is generally considered to be more potent than Roxicodone, which means that it can provide effective pain relief at lower doses.
  • Duration of Action: Opana is renowned for its extended duration of action, offering sustained pain relief over an extended period compared to the shorter duration of action associated with Roxicodone.
  • Formulations:Opana is available in various formulations, including extended-release forms, which release the medication gradually. This results in a steady level of pain relief. Roxicodone, on the other hand, is predominantly available in immediate-release formulations, providing rapid relief from pain but with a shorter-lasting effect.
  • Approved Uses: Opana is typically approved for the management of severe pain, often utilized post-surgery or for chronic pain conditions. Roxicodone is commonly prescribed for moderate to severe pain, including dental procedures, injuries, and post-operative pain.
  • Abuse Potential: Both Opana and Roxicodone share a high potential for abuse and addiction due to their opioid nature. Misuse can lead to euphoria, contributing to dependence.
  • Side Effects: Common side effects of both medications include dizziness, drowsiness, nausea, constipation, and, in cases of overdose, potentially life-threatening respiratory depression.

Use of Opana and Roxicodone in Medical Conditions:

It is crucial to understand how Opana and Roxicodone may be used in the context of various medical conditions:

  • Cancer Pain: Opana may be preferred in cases of severe cancer-related pain due to its potency and extended duration of action, providing continuous relief.
  • Chronic Pain: For individuals suffering from chronic pain conditions like arthritis or neuropathy, Roxicodone’s immediate-release formulation may offer quick relief when needed.
  • Post-Surgery: After surgical procedures, Opana’s extended-release formulation may be chosen to provide long-lasting pain management without frequent dosing.
  • Dental Procedures: Roxicodone’s rapid onset of action makes it a suitable choice for acute pain following dental surgery.

Tailored Treatment at New Hope Healthcare Institute:

At New Hope Healthcare Institute, we recognize the multifaceted nature of addiction to prescription opioids such as Opana and Roxicodone. Our comprehensive dual diagnosis treatment programs encompass:

  • Medically Supervised Detox: Under the watchful eye of our medical professionals, we ensure a safe detox process, managing withdrawal symptoms effectively.
  • Individualized Therapy: Personalized counseling and therapy sessions, designed to address the underlying causes of addiction and foster long-term recovery.
  • Supportive Environment: In our nurturing and understanding environment, you will find the strength and guidance to focus on your recovery journey.
  • Relapse Prevention: Equipped with coping skills and strategies, you will be better prepared to prevent relapse and maintain sobriety.
  • Aftercare: Our commitment to your recovery does not end with treatment; we provide continued support and resources for your successful journey.

Call New Hope Healthcare Institute!

If you or someone you care about is struggling with addiction to Opana, Roxicodone, or any other substance, we encourage you to reach out to us at New Hope Healthcare Institute. Our compassionate team is dedicated to guiding you towards recovery. Don’t wait any longer; take the first step by calling us at 866-806-1027. Check out our blog where we post weekly on Medium.


Yes, Opana is generally considered to be more potent than Roxicodone due to its ability to provide pain relief at lower doses.

Common side effects include dizziness, drowsiness, nausea, constipation, and, in extreme cases, respiratory depression.

Yes, even when prescribed by a healthcare professional, these medications carry a high potential for addiction if not used as directed.

Yes, your doctor can discuss alternative pain management options that may be suitable for your specific needs and conditions.

If you or someone you know is struggling with opioid addiction, reaching out to a professional treatment center like New Hope Healthcare Institute is a vital step towards recovery.

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