substance abuse10 min readJuly 23, 2026

Pregnancy and Opioid Use Disorder in Knoxville: Why MAT (Buprenorphine or Methadone) Is the Safest Path for Mom and Baby

Learn how pregnancy opioid use disorder treatment uses buprenorphine or methadone, prenatal care, counseling, and support to protect both mother and baby today.

NH

New Hope Health

Editorial Team

Pregnancy and Opioid Use Disorder in Knoxville: Why MAT (Buprenorphine or Methadone) Is the Safest Path for Mom and Baby

Pregnancy can make opioid addiction feel even more overwhelming, but effective treatment is available for pregnant women and their families.

Understanding the latest clinical guidance, substance use treatment options, and the role of prenatal care providers can help people make informed decisions that support healthier pregnancies and improved outcomes.

This guide explains what to know about pregnancy opioid use disorder treatment, medication-assisted treatment (MAT), and recovery before, during, and after delivery.

What Is Opioid Use Disorder During Pregnancy?

Opioid use disorder (OUD) during pregnancy is a treatable medical condition in which a person cannot control opioid use despite harmful effects.

It may involve:

  • Prescription pain medications
  • Heroin
  • Fentanyl
  • Other opioids

Opioid use disorder can cause:

  • Cravings
  • Tolerance
  • Physical dependence
  • Withdrawal symptoms

Treatment during pregnancy often includes:

  • Buprenorphine
  • Methadone
  • Prenatal care
  • Counseling
  • Behavioral health support

These services help protect both the mother and the developing baby.

How Opioid Use Affects the Mother and Developing Baby

Opioid use during pregnancy can affect both maternal health and fetal development.

Risks for the Mother

  • Overdose
  • Infection
  • Poor nutrition
  • Preterm labor
  • Pregnancy complications
  • Continued opioid dependence

Risks for the Baby

  • Poor fetal growth
  • Premature birth
  • Low birth weight
  • Stillbirth
  • Neonatal opioid withdrawal syndrome (NOWS)

Early treatment helps reduce these risks and supports healthier outcomes for both mother and baby.

Why Suddenly Stopping Opioids During Pregnancy Can Be Dangerous

Stopping opioids suddenly during pregnancy can cause:

  • Withdrawal
  • Severe cravings
  • Relapse
  • Increased overdose risk after reduced tolerance

Untreated opioid use disorder is associated with increased risks for both the mother and the developing baby.

Clinical guidelines recommend medication-assisted treatment rather than attempting withdrawal without medical supervision.

What Is Medication-Assisted Treatment During Pregnancy?

Medication-assisted treatment (MAT) is the recommended treatment for opioid use disorder during pregnancy.

MAT combines:

  • FDA-approved medications
  • Prenatal care
  • Counseling
  • Behavioral therapy
  • Recovery support

This approach helps stabilize opioid use while improving the health of both mother and baby.

Why Buprenorphine or Methadone Is the Safest Treatment Path

Buprenorphine and methadone are considered the standard treatments for opioid use disorder during pregnancy.

Unlike short-acting opioids that create repeated cycles of intoxication and withdrawal, these long-acting medications help provide stability.

Benefits include:

  • Reduced withdrawal symptoms
  • Fewer cravings
  • Reduced illicit opioid use
  • Lower relapse risk
  • Lower overdose risk
  • Improved treatment participation

Research consistently shows that remaining on medication-assisted treatment is much safer than continuing uncontrolled opioid use or attempting to quit without medical supervision.

Buprenorphine vs. Methadone During Pregnancy

Both medications are considered safe and effective, but each has unique advantages.

Buprenorphine

Buprenorphine:

  • May be prescribed in office-based settings
  • May reduce the severity of neonatal opioid withdrawal syndrome
  • Allows greater treatment flexibility

Methadone

Methadone:

  • Is provided through certified opioid treatment programs
  • May be recommended for severe opioid dependence
  • Offers additional structure through supervised treatment

The best medication depends on:

  • Medical history
  • Pregnancy status
  • Opioid use history
  • Recovery goals
  • Clinical recommendations

Benefits of MAT for the Mother and Baby

Medication-assisted treatment may:

  • Reduce opioid cravings
  • Reduce withdrawal symptoms
  • Lower relapse risk
  • Lower overdose risk
  • Improve prenatal care participation
  • Reduce illicit opioid use
  • Support healthier fetal growth
  • Improve birth outcomes
  • Increase treatment retention
  • Help prepare for labor and postpartum recovery
  • Connect families with counseling and recovery support

How MAT Protects Fetal Development and Pregnancy Outcomes

Medication-assisted treatment helps create a more stable pregnancy by preventing repeated cycles of opioid intoxication and withdrawal.

Consistent treatment supports:

  • Regular prenatal care
  • Better nutrition
  • Medical monitoring
  • Improved fetal development
  • Lower risk of premature birth
  • Lower risk of low birth weight
  • Reduced pregnancy complications

How MAT Reduces Withdrawal, Cravings, Overdose, and Relapse Risk

Buprenorphine and methadone stabilize opioid receptors in the brain.

This helps:

  • Prevent withdrawal
  • Reduce cravings
  • Lower illicit opioid use
  • Reduce overdose risk
  • Reduce relapse
  • Allow greater focus on prenatal care and recovery

Neonatal Opioid Withdrawal Syndrome and Newborn Care

Neonatal opioid withdrawal syndrome (NOWS), also called neonatal abstinence syndrome (NAS), can occur after prenatal opioid exposure.

Approximately 30% to 80% of opioid-exposed infants may experience withdrawal symptoms.

Symptoms may include:

  • Excessive crying
  • Tremors
  • Feeding difficulties
  • Sleep problems
  • Vomiting
  • Diarrhea
  • Irritability

Symptoms usually begin within 72 hours after birth.

Hospitals monitor affected newborns and provide:

  • Supportive care
  • Medication when needed
  • Feeding support
  • Ongoing observation

NOWS is an expected and treatable condition.

When appropriate, breastfeeding may reduce symptom severity, and most infants recover well with proper medical care.

Prevalence of Opioid Use Disorder During Pregnancy in Tennessee

Opioid use disorder during pregnancy remains a major public health concern throughout Tennessee and the United States.

Research has shown:

  • Opioid use during pregnancy increased 131% between 2010 and 2017.
  • Neonatal abstinence syndrome increased from 1.5 to 6.0 cases per 1,000 births.
  • More than 21,000 U.S. infants experienced opioid withdrawal in 2012.
  • Opioid use disorder affects approximately 2.7% of pregnant Medicaid recipients.

Although treatment rates have improved, medication-assisted treatment remains underused.

Major medical organizations continue to recommend opioid agonist therapy during pregnancy.

Effects and Risks of Untreated Opioid Use Disorder During Pregnancy

Short-Term Risks

  • Withdrawal
  • Severe cravings
  • Relapse
  • Overdose
  • Poor prenatal care
  • Infection
  • Malnutrition
  • Preterm labor
  • Fetal distress

Long-Term Risks

  • Continued opioid dependence
  • Maternal overdose
  • Maternal death
  • Poor birth outcomes
  • Neonatal opioid withdrawal syndrome
  • Ongoing mental health problems
  • Family instability

Prenatal Care, Counseling, and Behavioral Health Support

Regular prenatal care allows healthcare providers to monitor both the mother and the developing baby.

Providers may screen for substance use using validated screening tools.

Comprehensive care often includes:

  • Prenatal care
  • Counseling
  • Behavioral therapy
  • Medication management
  • Mental health services
  • HIV screening
  • Contraceptive counseling
  • Nutrition support
  • Recovery planning

Integrated care helps reduce:

  • High-risk behaviors
  • Birth complications
  • Relapse
  • Mental health symptoms

Co-Occurring Anxiety, Depression, PTSD, and Bipolar Disorder

Many pregnant patients with opioid use disorder also experience:

  • Anxiety
  • Depression
  • PTSD
  • Bipolar disorder
  • Other mood disorders

Untreated mental health conditions may increase:

  • Cravings
  • Relapse risk
  • Poor prenatal care
  • Overdose risk

Treating both addiction and mental health conditions together improves long-term recovery outcomes.

Warning Signs That Treatment Is Needed

Professional treatment should be considered when someone experiences:

  • Continued opioid use during pregnancy
  • Strong cravings
  • Withdrawal symptoms
  • Difficulty reducing opioid use
  • Increasing opioid doses
  • Missed prenatal appointments
  • Heroin use
  • Fentanyl use
  • Non-prescribed opioid use
  • Mixing opioids with alcohol
  • Mixing opioids with benzodiazepines
  • Previous overdose
  • Previous relapse
  • Anxiety
  • Depression
  • Suicidal thoughts
  • Concern expressed by family members

Relapse Prevention During Pregnancy and After Delivery

Relapse prevention strategies include:

  • Continuing prescribed buprenorphine or methadone
  • Attending counseling
  • Keeping prenatal appointments
  • Keeping postpartum appointments
  • Building a strong support system
  • Identifying triggers
  • Avoiding alcohol
  • Avoiding heroin
  • Avoiding fentanyl
  • Avoiding benzodiazepines
  • Avoiding other non-prescribed substances

The postpartum period carries an increased risk of relapse and overdose, making continued treatment especially important.

Labor, Delivery, Pain Management, and Breastfeeding While Receiving MAT

Most patients continue buprenorphine or methadone throughout labor and after delivery.

Healthcare providers develop individualized pain management plans that may include:

  • Non-opioid pain medications
  • Regional anesthesia
  • Carefully monitored opioid medications when medically necessary

Many patients can safely breastfeed while receiving medication-assisted treatment if they:

  • Remain stable in recovery
  • Are not using illicit opioids
  • Are not using cocaine
  • Are not using methamphetamine
  • Are not using other unsafe substances

Naltrexone during pregnancy requires individualized specialist evaluation.

Postpartum Depression, Anxiety, and Overdose Risk

The weeks and months after childbirth are considered a high-risk period for:

  • Postpartum depression
  • Anxiety
  • Relapse
  • Overdose

Contributing factors may include:

  • Sleep deprivation
  • Hormonal changes
  • Stress
  • Untreated mental health conditions

Continued medication-assisted treatment, counseling, mental healthcare, and family support help improve recovery and reduce overdose risk.

How Outpatient Treatment Supports Pregnant Patients

Outpatient treatment allows pregnant patients to receive comprehensive care while continuing daily responsibilities.

Services may include:

  • Medication management
  • Individual counseling
  • Group therapy
  • Relapse prevention
  • Behavioral health services
  • Prenatal care coordination
  • Mental health treatment
  • Recovery monitoring

Treatment plans are individualized based on:

  • Medical needs
  • Mental health conditions
  • Recovery goals
  • Pregnancy needs

When to Seek Help

Seek professional help as soon as:

  • Opioid use continues during pregnancy
  • Withdrawal symptoms develop
  • Cravings become difficult to manage
  • Mental health symptoms worsen

Early treatment improves the health and safety of both mother and baby.

Pregnancy Opioid Use Disorder Treatment Options

Medication-Assisted Treatment (MAT)

Buprenorphine or methadone combined with counseling and prenatal care remains the primary treatment approach.

Outpatient Treatment

Provides:

  • Individual therapy
  • Group counseling
  • Medication management
  • Relapse prevention

Intensive Outpatient Program (IOP)

Provides more structured therapy several days each week while allowing patients to live at home.

Behavioral Therapy

Behavioral therapy may include:

  • Cognitive Behavioral Therapy (CBT)
  • Motivational Interviewing (MI)
  • Trauma-informed therapy

Mental Health Treatment

Treats:

  • Anxiety
  • Depression
  • PTSD
  • Bipolar disorder
  • Other co-occurring mental health conditions

Prenatal and Postpartum Care

Regular medical visits monitor:

  • Maternal health
  • Fetal development
  • Postpartum recovery

Treatment approaches may differ from those used for non-pregnant patients.

Does Insurance Cover Treatment?

Many private insurance plans, TennCare, and Medicaid programs cover medically necessary pregnancy opioid use disorder treatment.

Coverage often includes:

  • Medication-assisted treatment
  • Prenatal care
  • Counseling
  • Behavioral health services
  • Outpatient addiction treatment
  • Mental health treatment

Benefits vary by individual insurance plan.

Conclusion

Treating opioid use disorder during pregnancy can reduce overdose risk, improve neonatal outcomes, and support healthier pregnancies.

Evidence-based addiction treatment, medication-assisted treatment, prenatal care, relapse prevention, and coordinated healthcare remain the standard of care for pregnant and postpartum patients.

If you or someone you love is living with opioid addiction during pregnancy, seeking treatment early can improve outcomes for both the mother and baby while supporting long-term recovery.

Seeking Treatment? We Can Help!

At New Hope Healthcare, we are an in-network provider and work with many insurance plans, including:

  • TRICARE
  • Magellan Health
  • First Health Network
  • Cigna
  • Anthem Blue Cross Blue Shield
  • Aetna
  • Humana
  • TriWest VA
  • UnitedHealthcare
  • Optum
  • UMR
  • Oscar
  • Celtic Insurance
  • Ambetter
  • And more

If you or a loved one is struggling with mental health challenges or substance abuse, seeking treatment and emotional support is important.

Consulting a doctor or treatment professional can provide the support and guidance needed to choose an appropriate level of care.

Reach out to New Hope Healthcare today. Our team of compassionate professionals is here to support your journey toward lasting well-being.

Effective medication management can be an important part of the treatment process and may help improve safety and long-term success.

Call us at 866-799-0806.

FAQs

What Is the Safest Treatment for Opioid Use Disorder During Pregnancy?

Medication-assisted treatment with buprenorphine or methadone, combined with prenatal care and counseling, is the recommended treatment for most pregnant patients.

Can You Stop Taking Opioids Suddenly While Pregnant?

No. Suddenly stopping opioids can trigger withdrawal, increase relapse risk, and may harm both the pregnancy and the developing baby. Treatment should always be supervised by a medical provider.

Will My Baby Have Withdrawal Symptoms After Birth?

Some babies develop neonatal opioid withdrawal syndrome after prenatal opioid exposure. Healthcare providers monitor newborns closely and provide treatment when needed.

People Also Ask

Is Buprenorphine or Methadone Better During Pregnancy?

Both medications are considered safe and effective. The best choice depends on the mother's medical history, opioid use, pregnancy, and treatment needs.

Can You Breastfeed While Taking Buprenorphine or Methadone?

In many cases, yes. Breastfeeding is often encouraged for stable patients unless there are other medical or substance use concerns.

Does Pregnancy Opioid Use Disorder Treatment Include Counseling?

Yes. Treatment commonly includes counseling, behavioral therapy, prenatal care, medication management, mental health treatment, and relapse prevention support.

Sources

  • American College of Obstetricians and Gynecologists (ACOG): Opioid Use and Opioid Use Disorder in Pregnancy
  • Centers for Disease Control and Prevention (CDC): Treatment of Opioid Use Disorder Before, During, and After Pregnancy
  • Substance Abuse and Mental Health Services Administration (SAMHSA): Treating Opioid Use Disorder During Pregnancy
  • Centers for Disease Control and Prevention (CDC): Treating Infants Affected by Prenatal Opioid Exposure
  • National Institute on Drug Abuse (NIDA): Substance Use While Pregnant and Breastfeeding

About the Author

New Hope Health

New Hope Health

Editorial Team

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